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Protein folding, misfolding and aggregation: The importance of two-electron stabilizing interactions
Proteins associated with neurodegenerative diseases are highly pleiomorphic and may adopt an all-α-helical fold in one environment, assemble into all-β-sheet or collapse into a coil in another, and rapidly polymerize in yet another one via divergent aggregation pathways that yield broad diversity of...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603215/ https://www.ncbi.nlm.nih.gov/pubmed/28922400 http://dx.doi.org/10.1371/journal.pone.0180905 |