Robust antibody and CD8(+) T-cell responses induced by P. falciparum CSP adsorbed to cationic liposomal adjuvant CAF09 confer sterilizing immunity against experimental rodent malaria infection

Despite several decades of extensive research, the development of a highly efficacious malaria vaccine has yet to be accomplished. While the RTS,S malaria vaccine candidate shows the potential to prevent a substantial number of clinical malaria cases, significant improvements in protective efficacy...

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Detalles Bibliográficos
Autores principales: Espinosa, Diego A., Christensen, Dennis, Muñoz, Christian, Singh, Sanjay, Locke, Emily, Andersen, Peter, Zavala, Fidel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603302/
https://www.ncbi.nlm.nih.gov/pubmed/28936360
http://dx.doi.org/10.1038/s41541-017-0011-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603302/
https://www.ncbi.nlm.nih.gov/pubmed/28936360
http://dx.doi.org/10.1038/s41541-017-0011-y

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