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Robust antibody and CD8(+) T-cell responses induced by P. falciparum CSP adsorbed to cationic liposomal adjuvant CAF09 confer sterilizing immunity against experimental rodent malaria infection
Despite several decades of extensive research, the development of a highly efficacious malaria vaccine has yet to be accomplished. While the RTS,S malaria vaccine candidate shows the potential to prevent a substantial number of clinical malaria cases, significant improvements in protective efficacy...
Autores principales: | Espinosa, Diego A., Christensen, Dennis, Muñoz, Christian, Singh, Sanjay, Locke, Emily, Andersen, Peter, Zavala, Fidel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603302/ https://www.ncbi.nlm.nih.gov/pubmed/28936360 http://dx.doi.org/10.1038/s41541-017-0011-y |
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