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Synthesis, molecular docking and biological evaluation of bis-pyrimidine Schiff base derivatives

BACKGROUND: Heterocyclic pyrimidine nucleus, which is an essential base component of the genetic material of deoxyribonucleic acid, demonstrated various biological activities. A series of bis-pyrimidine Schiff bases were synthesized and screened for its antimicrobial and anticancer potentials. The m...

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Detalles Bibliográficos
Autores principales: Kumar, Sanjiv, Lim, Siong Meng, Ramasamy, Kalavathy, Vasudevan, Mani, Shah, Syed Adnan Ali, Selvaraj, Manikandan, Narasimhan, Balasubramanian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603458/
https://www.ncbi.nlm.nih.gov/pubmed/29086867
http://dx.doi.org/10.1186/s13065-017-0322-0