Cargando…
Synthesis, molecular docking and biological evaluation of bis-pyrimidine Schiff base derivatives
BACKGROUND: Heterocyclic pyrimidine nucleus, which is an essential base component of the genetic material of deoxyribonucleic acid, demonstrated various biological activities. A series of bis-pyrimidine Schiff bases were synthesized and screened for its antimicrobial and anticancer potentials. The m...
Autores principales: | Kumar, Sanjiv, Lim, Siong Meng, Ramasamy, Kalavathy, Vasudevan, Mani, Shah, Syed Adnan Ali, Selvaraj, Manikandan, Narasimhan, Balasubramanian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603458/ https://www.ncbi.nlm.nih.gov/pubmed/29086867 http://dx.doi.org/10.1186/s13065-017-0322-0 |
Ejemplares similares
-
Bis-pyrimidine acetamides: design, synthesis and biological evaluation
por: Kumar, Sanjiv, et al.
Publicado: (2017) -
Molecular docking, synthesis and biological significance of pyrimidine analogues as prospective antimicrobial and antiproliferative agents
por: Kumar, Sanjiv, et al.
Publicado: (2019) -
Reverse pharmacophore mapping and molecular docking studies for discovery of GTPase HRas as promising drug target for bis-pyrimidine derivatives
por: Kumar, Sanjiv, et al.
Publicado: (2018) -
Design, synthesis, antimicrobial and cytotoxicity study on human colorectal carcinoma cell line of new 4,4′-(1,4-phenylene)bis(pyrimidin-2-amine) derivatives
por: Kumar, Sanjiv, et al.
Publicado: (2018) -
Synthesis, characterization, biological evaluation and molecular docking studies of 2-(1H-benzo[d]imidazol-2-ylthio)-N-(substituted 4-oxothiazolidin-3-yl) acetamides
por: Yadav, Snehlata, et al.
Publicado: (2017)