Dihydromyricetin-mediated inhibition of the Notch1 pathway induces apoptosis in QGY7701 and HepG2 hepatoma cells

AIM: To investigate whether Dihydromyricetin (DHM) inhibits cell proliferation and promotes apoptosis by downregulating Notch1 expression. METHODS: The correlation between Notch1 and Hes1 (a Notch1 target molecule) expression in hepatoma samples was confirmed by qRT-PCR. In addition, MTT assays, flo...

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Detalles Bibliográficos
Autores principales: Lu, Cai-Jie, He, Yi-Feng, Yuan, Wei-Zhuang, Xiang, Li-Jun, Zhang, Jian, Liang, Yan-Rui, Duan, Juan, He, Yun-He, Li, Ming-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603490/
https://www.ncbi.nlm.nih.gov/pubmed/28974890
http://dx.doi.org/10.3748/wjg.v23.i34.6242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603490/
https://www.ncbi.nlm.nih.gov/pubmed/28974890
http://dx.doi.org/10.3748/wjg.v23.i34.6242

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