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Curcumin inhibits hepatitis B virus infection by down-regulating cccDNA-bound histone acetylation

AIM: To investigate the potential effect of curcumin on hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) and the underlying mechanism. METHODS: A HepG2.2.15 cell line stably transfected with HBV was treated with curcumin, and HBV surface antigen (HBsAg) and e antigen (HBeAg) expressio...

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Detalles Bibliográficos
Autores principales: Wei, Zhi-Qiang, Zhang, Yong-Hong, Ke, Chang-Zheng, Chen, Hong-Xia, Ren, Pan, He, Yu-Lin, Hu, Pei, Ma, De-Qiang, Luo, Jie, Meng, Zhong-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603491/
https://www.ncbi.nlm.nih.gov/pubmed/28974891
http://dx.doi.org/10.3748/wjg.v23.i34.6252