Discovery, Semisynthesis, Antiparasitic and Cytotoxic Evaluation of 14-Membered Resorcylic Acid Lactones and Their Derivatives

Ten antifouling 14-membered resorcylic acid lactones 1–10 were isolated previously with low or trace natural abundance from the zoanthid-derived Cochliobolus lunatus fungus. Further optimization of fermentation conditions led to the isolation of two major natural compounds 7 and 8 with multi-gram qu...

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Detalles Bibliográficos
Autores principales: Zhang, Xue-Qing, Spadafora, Carmenza, Pineda, Laura M., Ng, Michelle G., Sun, Ji-Hong, Wang, Wei, Wang, Chang-Yun, Gu, Yu-Cheng, Shao, Chang-Lun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603512/
https://www.ncbi.nlm.nih.gov/pubmed/28924201
http://dx.doi.org/10.1038/s41598-017-12336-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603512/
https://www.ncbi.nlm.nih.gov/pubmed/28924201
http://dx.doi.org/10.1038/s41598-017-12336-0

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