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Discovery, Semisynthesis, Antiparasitic and Cytotoxic Evaluation of 14-Membered Resorcylic Acid Lactones and Their Derivatives

Ten antifouling 14-membered resorcylic acid lactones 1–10 were isolated previously with low or trace natural abundance from the zoanthid-derived Cochliobolus lunatus fungus. Further optimization of fermentation conditions led to the isolation of two major natural compounds 7 and 8 with multi-gram qu...

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Detalles Bibliográficos
Autores principales:	Zhang, Xue-Qing, Spadafora, Carmenza, Pineda, Laura M., Ng, Michelle G., Sun, Ji-Hong, Wang, Wei, Wang, Chang-Yun, Gu, Yu-Cheng, Shao, Chang-Lun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603512/ https://www.ncbi.nlm.nih.gov/pubmed/28924201 http://dx.doi.org/10.1038/s41598-017-12336-0

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