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Detrimental effect of Hypoxia-inducible factor-1α-induced autophagy on multiterritory perforator flap survival in rats

Hypoxia-inducible factor-1α (HIF-1α) plays a key role in angiogenesis, improves flap survival, and activates autophagy. The effect of HIF-1α-induced autophagy is still debatable. Thus, we investigated the effect of HIF-1α-induced autophagy on multiterritory perforator flap survival. In this study, 9...

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Detalles Bibliográficos
Autores principales: Wang, Long, Jin, Zhicheng, Wang, Jieke, Chen, Shao, Dai, Li, Lin, Dingsheng, Wu, Lingfeng, Gao, Weiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603514/
https://www.ncbi.nlm.nih.gov/pubmed/28924179
http://dx.doi.org/10.1038/s41598-017-12034-x