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Loss of MAPK-activated protein kinase 2 enables potent dendritic cell-driven anti-tumour T cell response
Maintaining dendritic cells (DC) in a state of dysfunction represents a key mechanism by which tumour cells evade recognition and elimination by the immune system. Limited knowledge about the intracellular mediators of DC dysfunction restricts success of therapies aimed at reactivating a DC-driven a...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603533/ https://www.ncbi.nlm.nih.gov/pubmed/28924177 http://dx.doi.org/10.1038/s41598-017-12208-7 |