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Loss of MAPK-activated protein kinase 2 enables potent dendritic cell-driven anti-tumour T cell response

Maintaining dendritic cells (DC) in a state of dysfunction represents a key mechanism by which tumour cells evade recognition and elimination by the immune system. Limited knowledge about the intracellular mediators of DC dysfunction restricts success of therapies aimed at reactivating a DC-driven a...

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Detalles Bibliográficos
Autores principales: Soukup, Klara, Halfmann, Angela, Dillinger, Barbara, Poyer, Fiona, Martin, Katharina, Blauensteiner, Bernadette, Kauer, Maximilian, Kuttke, Mario, Schabbauer, Gernot, Dohnal, Alexander M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603533/
https://www.ncbi.nlm.nih.gov/pubmed/28924177
http://dx.doi.org/10.1038/s41598-017-12208-7