Cargando…

Novel ecto-tagged integrins reveal their trafficking in live cells

Integrins are abundant heterodimeric cell-surface adhesion receptors essential in multicellular organisms. Integrin function is dynamically modulated by endo-exocytic trafficking, however, major mysteries remain about where, when, and how this occurs in living cells. To address this, here we report...

Descripción completa

Detalles Bibliográficos
Autores principales: Huet-Calderwood, Clotilde, Rivera-Molina, Felix, Iwamoto, Daniel V., Kromann, Emil B., Toomre, Derek, Calderwood, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603536/
https://www.ncbi.nlm.nih.gov/pubmed/28924207
http://dx.doi.org/10.1038/s41467-017-00646-w