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Short chain fatty acids ameliorate immune-mediated uveitis partially by altering migration of lymphocytes from the intestine

Short chain fatty acids (SCFA) are metabolites of intestinal bacteria resulting from fermentation of dietary fiber. SCFA are protective in various animal models of inflammatory disease. We investigated the effects of exogenous administration of SFCAs, particularly propionate, on uveitis using an ind...

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Detalles Bibliográficos
Autores principales: Nakamura, Yukiko K., Janowitz, Cathleen, Metea, Christina, Asquith, Mark, Karstens, Lisa, Rosenbaum, James T., Lin, Phoebe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603543/
https://www.ncbi.nlm.nih.gov/pubmed/28924192
http://dx.doi.org/10.1038/s41598-017-12163-3