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The ClpXP protease is dispensable for degradation of unfolded proteins in Staphylococcus aureus

In living cells intracellular proteolysis is crucial for protein homeostasis, and ClpP proteases are conserved between eubacteria and the organelles of eukaryotic cells. In Staphylococcus aureus, ClpP associates to the substrate specificity factors, ClpX and ClpC forming two ClpP proteases, ClpXP an...

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Detalles Bibliográficos
Autores principales: Stahlhut, Steen G., Alqarzaee, Abdulelah A., Jensen, Camilla, Fisker, Niclas S., Pereira, Ana R., Pinho, Mariana G., Thomas, Vinai Chittezham, Frees, Dorte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603545/
https://www.ncbi.nlm.nih.gov/pubmed/28924169
http://dx.doi.org/10.1038/s41598-017-12122-y