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Conjugation of wildtype and hypoallergenic mugwort allergen Art v 1 to flagellin induces IL-10-DC and suppresses allergen-specific TH2-responses in vivo

Allergies to weed pollen including members of the Compositae family, such as mugwort, ragweed, and feverfew are spreading worldwide. To efficiently treat these newly arising allergies, allergen specific immunotherapy needs to be improved. Therefore, we generated novel vaccine candidates consisting o...

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Detalles Bibliográficos
Autores principales: Schülke, Stefan, Kuttich, Kirsten, Wolfheimer, Sonja, Duschek, Nadine, Wangorsch, Andrea, Reuter, Andreas, Briza, Peter, Pablos, Isabel, Gadermaier, Gabriele, Ferreira, Fatima, Vieths, Stefan, Toda, Masako, Scheurer, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603567/
https://www.ncbi.nlm.nih.gov/pubmed/28924222
http://dx.doi.org/10.1038/s41598-017-11972-w