Mesoscopic model for DNA G-quadruplex unfolding

Genomes contain rare guanine-rich sequences capable of assembling into four-stranded helical structures, termed G-quadruplexes, with potential roles in gene regulation and chromosome stability. Their mechanical unfolding has only been reported to date by all-atom simulations, which cannot dissect th...

Descripción completa

Detalles Bibliográficos
Autores principales: Bergues-Pupo, A. E., Gutiérrez, I., Arias-Gonzalez, J. R., Falo, F., Fiasconaro, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603602/
https://www.ncbi.nlm.nih.gov/pubmed/28924219
http://dx.doi.org/10.1038/s41598-017-10849-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603602/
https://www.ncbi.nlm.nih.gov/pubmed/28924219
http://dx.doi.org/10.1038/s41598-017-10849-2

Ejemplares similares