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Strong Clonal Relatedness between Serum and Gut IgA despite Different Plasma Cell Origins
Mucosal antigens induce generation of lamina propria plasma cells (PCs) that secrete dimeric immunoglobulin A (IgA) destined for transport across the epithelium. In addition, blood contains monomeric IgA. To study the relationship between mucosal and systemic antibody responses, we took advantage of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603730/ https://www.ncbi.nlm.nih.gov/pubmed/28877470 http://dx.doi.org/10.1016/j.celrep.2017.08.036 |