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Strong Clonal Relatedness between Serum and Gut IgA despite Different Plasma Cell Origins

Mucosal antigens induce generation of lamina propria plasma cells (PCs) that secrete dimeric immunoglobulin A (IgA) destined for transport across the epithelium. In addition, blood contains monomeric IgA. To study the relationship between mucosal and systemic antibody responses, we took advantage of...

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Detalles Bibliográficos
Autores principales: Iversen, Rasmus, Snir, Omri, Stensland, Maria, Kroll, José E., Steinsbø, Øyvind, Korponay-Szabó, Ilma R., Lundin, Knut E.A., de Souza, Gustavo A., Sollid, Ludvig M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603730/
https://www.ncbi.nlm.nih.gov/pubmed/28877470
http://dx.doi.org/10.1016/j.celrep.2017.08.036