Cargando…

Strong Clonal Relatedness between Serum and Gut IgA despite Different Plasma Cell Origins

Mucosal antigens induce generation of lamina propria plasma cells (PCs) that secrete dimeric immunoglobulin A (IgA) destined for transport across the epithelium. In addition, blood contains monomeric IgA. To study the relationship between mucosal and systemic antibody responses, we took advantage of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iversen, Rasmus, Snir, Omri, Stensland, Maria, Kroll, José E., Steinsbø, Øyvind, Korponay-Szabó, Ilma R., Lundin, Knut E.A., de Souza, Gustavo A., Sollid, Ludvig M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603730/ https://www.ncbi.nlm.nih.gov/pubmed/28877470 http://dx.doi.org/10.1016/j.celrep.2017.08.036

Ejemplares similares

Restricted VH/VL usage and limited mutations in gluten-specific IgA of coeliac disease lesion plasma cells
por: Steinsbø, Øyvind, et al.
Publicado: (2014)

Longevity, clonal relationship, and transcriptional program of celiac disease–specific plasma cells
por: Lindeman, Ida, et al.
Publicado: (2020)

Gluten-specific antibodies of celiac disease gut plasma cells recognize long proteolytic fragments that typically harbor T-cell epitopes
por: Dørum, Siri, et al.
Publicado: (2016)

Pathogenic T Cells in Celiac Disease Change Phenotype on Gluten Challenge: Implications for T‐Cell‐Directed Therapies
por: Christophersen, Asbjørn, et al.
Publicado: (2021)

Pathogenic T Cells in Celiac Disease Change Phenotype on Gluten Challenge: Implications for T‐Cell‐Directed Therapies
por: Christophersen, Asbjørn, et al.
Publicado: (2022)

Abundance and unique repertoire of plasma cells secreting IgA autoantibodies to transglutaminase 2 in the intestinal lesion of celiac disease
por: Di Niro, Roberto, et al.
Publicado: (2012)

In Well‐Treated Celiac Patients Low‐Level Mucosal Inflammation Predicts Response to 14‐day Gluten Challenge
por: Stamnaes, Jorunn, et al.
Publicado: (2021)

Increased frequency of intestinal CD4(+) T cells reactive with mycobacteria in patients with Crohn's disease
por: Olsen, Ingrid, et al.
Publicado: (2013)

Thioredoxin Is Involved in Endothelial Cell Extracellular Transglutaminase 2 Activation Mediated by Celiac Disease Patient IgA
por: Antonella Nadalutti, Cristina, et al.
Publicado: (2013)

Polymorphisms in human immunoglobulin heavy chain variable genes and their upstream regions
por: Mikocziova, Ivana, et al.
Publicado: (2020)

Celiac Disease-Type Tissue Transglutaminase Autoantibody Deposits in Kidney Biopsies of Patients with IgA Nephropathy
por: Nurmi, Rakel, et al.
Publicado: (2021)

Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization
por: Bemark, Mats, et al.
Publicado: (2016)

Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping
por: Gidoni, Moriah, et al.
Publicado: (2019)

Anti-PAD4 autoantibodies in rheumatoid arthritis: levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate
por: Pollmann, Sylvie, et al.
Publicado: (2011)

A test for clonal relatedness in a set of lymphocytes
Publicado: (1990)

Clonal relatedness in tumour pairs of breast cancer patients
por: Biermann, Jana, et al.
Publicado: (2018)

Machine Learning Analysis of Naïve B-Cell Receptor Repertoires Stratifies Celiac Disease Patients and Controls
por: Shemesh, Or, et al.
Publicado: (2021)

Expression of transglutaminase 2 in human gut epithelial cells: Implications for coeliac disease
por: Amundsen, Sunniva F., et al.
Publicado: (2023)

Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3
por: Heggelund, Julie Elisabeth, et al.
Publicado: (2023)

Secretion of celiac disease autoantibodies after in vitro gliadin challenge is dependent on small-bowel mucosal transglutaminase 2-specific IgA deposits
por: Stenman, Satumarja M, et al.
Publicado: (2008)

PB1860: CLONALITY RELATEDNESS AND MOLECULAR CHARACTERISTICS OF RICHTER SYNDROME
por: Sha, Y., et al.
Publicado: (2022)

Identification of gluten T cell epitopes driving celiac disease
por: Chlubnová, Markéta, et al.
Publicado: (2023)

Separate Gut Plasma Cell Populations Produce Auto‐Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis
por: Das, Saykat, et al.
Publicado: (2023)

Enhanced B-Cell Receptor Recognition of the Autoantigen Transglutaminase 2 by Efficient Catalytic Self-Multimerization
por: Stamnaes, Jorunn, et al.
Publicado: (2015)

The Molecular Basis for Oat Intolerance in Patients with Celiac Disease
por: Arentz-Hansen, Helene, et al.
Publicado: (2004)

The Intestinal T Cell Response to α-Gliadin in Adult Celiac Disease Is Focused on a Single Deamidated Glutamine Targeted by Tissue Transglutaminase
por: Arentz-Hansen, Helene, et al.
Publicado: (2000)

Clonal relatedness between lobular carcinoma in situ and synchronous malignant lesions
por: Andrade, Victor P, et al.
Publicado: (2012)

Mutational signature and clonal relatedness of recurrent urothelial carcinomas with aristolochic acid
por: Zhu, Jie, et al.
Publicado: (2022)

Frequency of Gluten-Reactive T Cells in Active Celiac Lesions Estimated by Direct Cell Cloning
por: Qiao, Shuo-Wang, et al.
Publicado: (2021)

Phenotype‐Based Isolation of Antigen‐Specific CD4(+) T Cells in Autoimmunity: A Study of Celiac Disease
por: Christophersen, Asbjørn, et al.
Publicado: (2022)

Characterization of globulin storage proteins of a low prolamin cereal species in relation to celiac disease
por: Gell, Gyöngyvér, et al.
Publicado: (2017)

Transglutaminase 2 in human diseases
por: Szondy, Zsuzsa, et al.
Publicado: (2017)

Determination of lower cut‐off levels of adalimumab associated with biochemical remission in Crohn's disease
por: Carlsen, Arne, et al.
Publicado: (2019)

Molecular analysis of immunoglobulin genes reveals frequent clonal relatedness in double monoclonal gammopathies
por: Tschumper, R C, et al.
Publicado: (2013)

An EM algorithm to improve the estimation of the probability of clonal relatedness of pairs of tumors in cancer patients
por: Mauguen, Audrey, et al.
Publicado: (2019)

Rapid Accumulation of CD14(+)CD11c(+) Dendritic Cells in Gut Mucosa of Celiac Disease after in vivo Gluten Challenge
por: Beitnes, Ann-Christin Røberg, et al.
Publicado: (2012)

Biochemical Characterisation of Human Transglutaminase 4
por: Csobán-Szabó, Zsuzsa, et al.
Publicado: (2021)

Clonal Relatedness among Imipenem-Resistant Pseudomonas aeruginosa Isolated from ICU-Hospitalized Patients
por: Vaez, Hamid, et al.
Publicado: (2015)

Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease
por: Chen, Xi, et al.
Publicado: (2015)

Isolation of Mycobacterium avium Subspecies paratuberculosis Reactive CD4 T Cells from Intestinal Biopsies of Crohn's Disease Patients
por: Olsen, Ingrid, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_6ck0tdtdmt2u2npiio5a4plvjr