miR-494 up-regulates the PI3K/Akt pathway via targetting PTEN and attenuates hepatic ischemia/reperfusion injury in a rat model

A rat HIRI model was constructed and treated with an intraperitoneal injection of agomir-miR-494 or agomir-NC (negative control) for 7 days after the surgery. The pathophysiological changes in sham-operated rats, HIRI, HIRI + agomir-miR-494, and HIRI + agomir-NC were compared. The effect of miR-494...

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Detalles Bibliográficos
Autores principales: Su, Song, Luo, De, Liu, Xiangdong, Liu, Jiang, Peng, Fangyi, Fang, Cheng, Li, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603753/
https://www.ncbi.nlm.nih.gov/pubmed/28842516
http://dx.doi.org/10.1042/BSR20170798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603753/
https://www.ncbi.nlm.nih.gov/pubmed/28842516
http://dx.doi.org/10.1042/BSR20170798

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