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Osteocyte physiology and response to fluid shear stress are impaired following exposure to cobalt and chromium: Implications for bone health following joint replacement

The effects of metal ion exposure on osteocytes, the most abundant cell type in bone and responsible for coordinating bone remodeling, remain unclear. However, several studies have previously shown that exposure to cobalt (Co(2+)) and chromium (Cr(3+)), at concentrations equivalent to those found cl...

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Detalles Bibliográficos
Autores principales: Shah, Karan M., Orton, Peter, Mani, Nick, Wilkinson, Jeremy Mark, Gartland, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603770/
https://www.ncbi.nlm.nih.gov/pubmed/27673573
http://dx.doi.org/10.1002/jor.23449