Novel Method for High-Throughput Full-Length IGHV-D-J Sequencing of the Immune Repertoire from Bulk B-Cells with Single-Cell Resolution

Efficient and accurate high-throughput DNA sequencing of the adaptive immune receptor repertoire (AIRR) is necessary to study immune diversity in healthy subjects and disease-related conditions. The high complexity and diversity of the AIRR coupled with the limited amount of starting material, which...

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Detalles Bibliográficos
Autores principales: Vergani, Stefano, Korsunsky, Ilya, Mazzarello, Andrea Nicola, Ferrer, Gerardo, Chiorazzi, Nicholas, Bagnara, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603803/
https://www.ncbi.nlm.nih.gov/pubmed/28959265
http://dx.doi.org/10.3389/fimmu.2017.01157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603803/
https://www.ncbi.nlm.nih.gov/pubmed/28959265
http://dx.doi.org/10.3389/fimmu.2017.01157

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