QSAR Modeling of COX -2 Inhibitory Activity of Some Dihydropyridine and Hydroquinoline Derivatives Using Multiple Linear Regression (MLR) Method

COX-2 inhibitory activities of some 1,4-dihydropyridine and 5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives were modeled by quantitative structure–activity relationship (QSAR) using stepwise-multiple linear regression (SW-MLR) method. The built model was robust and predictive with correlation coeff...

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Detalles Bibliográficos
Autores principales: Akbari, Somaye, Zebardast, Tannaz, Zarghi, Afshin, Hajimahdi, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603861/
https://www.ncbi.nlm.nih.gov/pubmed/28979307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603861/
https://www.ncbi.nlm.nih.gov/pubmed/28979307

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