Transmembrane Helices Are an Overlooked Source of Major Histocompatibility Complex Class I Epitopes

About a fourth of the human proteome is anchored by transmembrane helices (TMHs) to lipid membranes. TMHs require multiple hydrophobic residues for spanning membranes, and this shows a striking resemblance with the requirements for peptide binding to major histocompatibility complex (MHC) class I. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Bianchi, Frans, Textor, Johannes, van den Bogaart, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604083/
https://www.ncbi.nlm.nih.gov/pubmed/28959259
http://dx.doi.org/10.3389/fimmu.2017.01118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604083/
https://www.ncbi.nlm.nih.gov/pubmed/28959259
http://dx.doi.org/10.3389/fimmu.2017.01118

Ejemplares similares