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Aberrant Cortical Activity in Multiple GCaMP6-Expressing Transgenic Mouse Lines

Transgenic mouse lines are invaluable tools for neuroscience but, as with any technique, care must be taken to ensure that the tool itself does not unduly affect the system under study. Here we report aberrant electrical activity, similar to interictal spikes, and accompanying fluorescence events in...

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Detalles Bibliográficos
Autores principales: Steinmetz, Nicholas A., Buetfering, Christina, Lecoq, Jerome, Lee, Christian R., Peters, Andrew J., Jacobs, Elina A. K., Coen, Philip, Ollerenshaw, Douglas R., Valley, Matthew T., de Vries, Saskia E. J., Garrett, Marina, Zhuang, Jun, Groblewski, Peter A., Manavi, Sahar, Miles, Jesse, White, Casey, Lee, Eric, Griffin, Fiona, Larkin, Joshua D., Roll, Kate, Cross, Sissy, Nguyen, Thuyanh V., Larsen, Rachael, Pendergraft, Julie, Daigle, Tanya, Tasic, Bosiljka, Thompson, Carol L., Waters, Jack, Olsen, Shawn, Margolis, David J., Zeng, Hongkui, Hausser, Michael, Carandini, Matteo, Harris, Kenneth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604087/
https://www.ncbi.nlm.nih.gov/pubmed/28932809
http://dx.doi.org/10.1523/ENEURO.0207-17.2017