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5-hydroxymethylcytosine is highly dynamic across human fetal brain development

BACKGROUND: Epigenetic processes play a key role in orchestrating transcriptional regulation during the development of the human central nervous system. We previously described dynamic changes in DNA methylation (5mC) occurring during human fetal brain development, but other epigenetic processes ope...

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Detalles Bibliográficos
Autores principales: Spiers, Helen, Hannon, Eilis, Schalkwyk, Leonard C., Bray, Nicholas J., Mill, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604137/
https://www.ncbi.nlm.nih.gov/pubmed/28923016
http://dx.doi.org/10.1186/s12864-017-4091-x