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Checkpoint inhibitor is active against large cell neuroendocrine carcinoma with high tumor mutation burden
BACKGROUND: Large cell neuroendocrine tumor (LCNEC) of the lung is a rare and aggressive tumor similar to small cell lung cancer (SCLC). Thus, it is often treated similarly to SCLC in the front-line setting with a platinum doublet. However, treatment for patients beyond the first line remains undefi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604145/ https://www.ncbi.nlm.nih.gov/pubmed/28923100 http://dx.doi.org/10.1186/s40425-017-0281-y |