Heterochromatin Reduction Correlates with the Increase of the KDM4B and KDM6A Demethylases and the Expression of Pericentromeric DNA during the Acquisition of a Transformed Phenotype

Cancer cells have alterations in chromatin organization, mostly a reduction in heterochromatin. How this process occurs during transformation and if it participates in the maintenance of a cancerous phenotype is not well understood. Here, using a transformation-inducible cell line, we analyzed the c...

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Detalles Bibliográficos
Autores principales: Gurrion, Cinthya, Uriostegui, Maritere, Zurita, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604219/
https://www.ncbi.nlm.nih.gov/pubmed/28928876
http://dx.doi.org/10.7150/jca.19477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604219/
https://www.ncbi.nlm.nih.gov/pubmed/28928876
http://dx.doi.org/10.7150/jca.19477

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