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Methods for discovering genomic loci exhibiting complex patterns of differential methylation

BACKGROUND: Cytosine methylation is widespread in most eukaryotic genomes and is known to play a substantial role in various regulatory pathways. Unmethylated cytosines may be converted to uracil through the addition of sodium bisulphite, allowing genome-wide quantification of cytosine methylation v...

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Detalles Bibliográficos
Autor principal: Hardcastle, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604413/
https://www.ncbi.nlm.nih.gov/pubmed/28923005
http://dx.doi.org/10.1186/s12859-017-1836-0