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Methods for discovering genomic loci exhibiting complex patterns of differential methylation
BACKGROUND: Cytosine methylation is widespread in most eukaryotic genomes and is known to play a substantial role in various regulatory pathways. Unmethylated cytosines may be converted to uracil through the addition of sodium bisulphite, allowing genome-wide quantification of cytosine methylation v...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604413/ https://www.ncbi.nlm.nih.gov/pubmed/28923005 http://dx.doi.org/10.1186/s12859-017-1836-0 |