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Endoplasmic reticulum stress cooperates with Toll-like receptor ligation in driving activation of rheumatoid arthritis fibroblast-like synoviocytes

BACKGROUND: Endoplasmic reticulum (ER) stress has proinflammatory properties, and transgenic animal studies of rheumatoid arthritis (RA) indicate its relevance in the process of joint destruction. Because currently available studies are focused primarily on myeloid cells, we assessed how ER stress m...

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Detalles Bibliográficos
Autores principales: Kabala, Pawel A., Angiolilli, Chiara, Yeremenko, Nataliya, Grabiec, Aleksander M., Giovannone, Barbara, Pots, Desiree, Radstake, Timothy R., Baeten, Dominique, Reedquist, Kris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604427/
https://www.ncbi.nlm.nih.gov/pubmed/28923079
http://dx.doi.org/10.1186/s13075-017-1386-x