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Endoplasmic reticulum stress cooperates with Toll-like receptor ligation in driving activation of rheumatoid arthritis fibroblast-like synoviocytes
BACKGROUND: Endoplasmic reticulum (ER) stress has proinflammatory properties, and transgenic animal studies of rheumatoid arthritis (RA) indicate its relevance in the process of joint destruction. Because currently available studies are focused primarily on myeloid cells, we assessed how ER stress m...
Autores principales: | Kabala, Pawel A., Angiolilli, Chiara, Yeremenko, Nataliya, Grabiec, Aleksander M., Giovannone, Barbara, Pots, Desiree, Radstake, Timothy R., Baeten, Dominique, Reedquist, Kris A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604427/ https://www.ncbi.nlm.nih.gov/pubmed/28923079 http://dx.doi.org/10.1186/s13075-017-1386-x |
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