RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury

The molecular pathways that regulate the tissue repair function of type I interferon (IFN-I) during acute tissue damage are poorly understood. We describe a protective role for IFN-I and the RIG-I/MAVS signaling pathway during acute tissue damage in mice. Mice lacking mitochondrial antiviral-signali...

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Detalles Bibliográficos
Autores principales: Fischer, Julius C., Bscheider, Michael, Eisenkolb, Gabriel, Lin, Chia-Ching, Wintges, Alexander, Otten, Vera, Lindemans, Caroline A., Heidegger, Simon, Rudelius, Martina, Monette, Sébastien, Porosnicu Rodriguez, Kori A., Calafiore, Marco, Liebermann, Sophie, Liu, Chen, Lienenklaus, Stefan, Weiss, Siegfried, Kalinke, Ulrich, Ruland, Jürgen, Peschel, Christian, Shono, Yusuke, Docampo, Melissa, Velardi, Enrico, Jenq, Robert R., Hanash, Alan M., Dudakov, Jarrod A., Haas, Tobias, van den Brink, Marcel R. M., Poeck, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604790/
https://www.ncbi.nlm.nih.gov/pubmed/28424327
http://dx.doi.org/10.1126/scitranslmed.aag2513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604790/
https://www.ncbi.nlm.nih.gov/pubmed/28424327
http://dx.doi.org/10.1126/scitranslmed.aag2513

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