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Liver X receptor activation promotes differentiation of regulatory T cells

The nuclear receptor Liver X Receptor (LXR) is a ligand-activated transcription factor that has been implicated in control of chronic inflammation by downregulating pro-inflammatory T cell responses. An impaired function of regulatory T cells, a subset of CD4+ T cells with a crucial role in maintain...

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Detalles Bibliográficos
Autores principales: Herold, Martin, Breuer, Johanna, Hucke, Stephanie, Knolle, Percy, Schwab, Nicholas, Wiendl, Heinz, Klotz, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604992/
https://www.ncbi.nlm.nih.gov/pubmed/28926619
http://dx.doi.org/10.1371/journal.pone.0184985