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Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways

Early events in the human airways determining whether exposure to Mycobacterium tuberculosis (Mtb) results in acquisition of infection are poorly understood. Epithelial cells are the dominant cell type in the lungs, but little is known about their role in tuberculosis. We hypothesised that human pri...

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Detalles Bibliográficos
Autores principales: Reuschl, Ann-Kathrin, Edwards, Michael R., Parker, Robert, Connell, David W., Hoang, Long, Halliday, Alice, Jarvis, Hannah, Siddiqui, Nazneen, Wright, Corrina, Bremang, Samuel, Newton, Sandra M., Beverley, Peter, Shattock, Robin J., Kon, Onn Min, Lalvani, Ajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605092/
https://www.ncbi.nlm.nih.gov/pubmed/28863187
http://dx.doi.org/10.1371/journal.ppat.1006577