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A transgenic toolkit for visualizing and perturbing microtubules reveals unexpected functions in the epidermis

The physiological functions of microtubules (MTs) are poorly understood in many differentiated cell types. We developed a genetic toolkit to study MT dynamics and function in diverse cells. Using TRE-EB1-GFP mice, we found that MT dynamics are strongly suppressed in differentiated keratinocytes in t...

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Detalles Bibliográficos
Autores principales: Muroyama, Andrew, Lechler, Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605193/
https://www.ncbi.nlm.nih.gov/pubmed/28869035
http://dx.doi.org/10.7554/eLife.29834