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BMPs direct sensory interneuron identity in the developing spinal cord using signal-specific not morphogenic activities

The Bone Morphogenetic Protein (BMP) family reiteratively signals to direct disparate cellular fates throughout embryogenesis. In the developing dorsal spinal cord, multiple BMPs are required to specify sensory interneurons (INs). Previous studies suggested that the BMPs act as concentration-depende...

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Detalles Bibliográficos
Autores principales: Andrews, Madeline G, del Castillo, Lorenzo M, Ochoa-Bolton, Eliana, Yamauchi, Ken, Smogorzewski, Jan, Butler, Samantha J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605194/
https://www.ncbi.nlm.nih.gov/pubmed/28925352
http://dx.doi.org/10.7554/eLife.30647