Deacetylation of topoisomerase I is an important physiological function of E. coli CobB

Escherichia coli topoisomerase I (TopA), a regulator of global and local DNA supercoiling, is modified by N(ε)-Lysine acetylation. The NAD(+)-dependent protein deacetylase CobB can reverse both enzymatic and non-enzymatic lysine acetylation modification in E. coli. Here, we show that the absence of...

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Detalles Bibliográficos
Autores principales: Zhou, Qingxuan, Zhou, Yan Ning, Jin, Ding Jun, Tse-Dinh, Yuk-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605244/
https://www.ncbi.nlm.nih.gov/pubmed/28398568
http://dx.doi.org/10.1093/nar/gkx250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605244/
https://www.ncbi.nlm.nih.gov/pubmed/28398568
http://dx.doi.org/10.1093/nar/gkx250

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