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Deacetylation of topoisomerase I is an important physiological function of E. coli CobB
Escherichia coli topoisomerase I (TopA), a regulator of global and local DNA supercoiling, is modified by N(ε)-Lysine acetylation. The NAD(+)-dependent protein deacetylase CobB can reverse both enzymatic and non-enzymatic lysine acetylation modification in E. coli. Here, we show that the absence of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605244/ https://www.ncbi.nlm.nih.gov/pubmed/28398568 http://dx.doi.org/10.1093/nar/gkx250 |