Bisulfite-independent analysis of CpG island methylation enables genome-scale stratification of single cells

Conventional DNA bisulfite sequencing has been extended to single cell level, but the coverage consistency is insufficient for parallel comparison. Here we report a novel method for genome-wide CpG island (CGI) methylation sequencing for single cells (scCGI-seq), combining methylation-sensitive rest...

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Detalles Bibliográficos
Autores principales: Han, Lin, Wu, Hua-Jun, Zhu, Haiying, Kim, Kun-Yong, Marjani, Sadie L., Riester, Markus, Euskirchen, Ghia, Zi, Xiaoyuan, Yang, Jennifer, Han, Jasper, Snyder, Michael, Park, In-Hyun, Irizarry, Rafael, Weissman, Sherman M., Michor, Franziska, Fan, Rong, Pan, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605247/
https://www.ncbi.nlm.nih.gov/pubmed/28126923
http://dx.doi.org/10.1093/nar/gkx026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605247/
https://www.ncbi.nlm.nih.gov/pubmed/28126923
http://dx.doi.org/10.1093/nar/gkx026

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