Cargando…

Truncated ORF1 proteins can suppress LINE-1 retrotransposition in trans

Long interspersed element 1 (L1) is an autonomous non-LTR retroelement that is active in mammalian genomes. Although retrotranspositionally incompetent and functional L1 loci are present in the same genomes, it remains unknown whether non-functional L1s have any trans effect on mobilization of activ...

Descripción completa

Detalles Bibliográficos
Autores principales: Sokolowski, Mark, Chynces, May, deHaro, Dawn, Christian, Claiborne M., Belancio, Victoria P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605252/
https://www.ncbi.nlm.nih.gov/pubmed/28431148
http://dx.doi.org/10.1093/nar/gkx211