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Reversion of High-level Mecillinam Resistance to Susceptibility in Escherichia coli During Growth in Urine

Mecillinam (amdinocillin) is a β-lactam antibiotic used to treat uncomplicated urinary tract infections (UTIs). We have previously shown that inactivation of the Escherichia coli cysB gene is the major cause of mecillinam resistance (Mec(R)) in clinical isolates. In this study, we used different E....

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Detalles Bibliográficos
Autores principales: Thulin, Elisabeth, Thulin, Måns, Andersson, Dan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605379/
https://www.ncbi.nlm.nih.gov/pubmed/28855073
http://dx.doi.org/10.1016/j.ebiom.2017.08.021