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Highly Selective Activation of Heat Shock Protein 70 by Allosteric Regulation Provides an Insight into Efficient Neuroinflammation Inhibition

Heat shock protein 70 (Hsp70) is widely involved in immune disorders, making it as an attractive drug target for inflammation diseases. Nonselective induction of Hsp70 upregulation for inflammation therapy could cause extensive interference in inflammation-unrelated protein functions, potentially re...

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Detalles Bibliográficos
Autores principales: Wang, Li-Chao, Liao, Li-Xi, Lv, Hai-Ning, Liu, Dan, Dong, Wei, Zhu, Jian, Chen, Jin-Feng, Shi, Meng-Ling, Fu, Ge, Song, Xiao-Min, Jiang, Yong, Zeng, Ke-Wu, Tu, Peng-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605382/
https://www.ncbi.nlm.nih.gov/pubmed/28807514
http://dx.doi.org/10.1016/j.ebiom.2017.08.011