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Study on pharmacokinetics and tissue distribution of single dose oral tryptanthrin in Kunming mice by validated reversed-phase high-performance liquid chromatography with ultraviolet detection

BACKGROUND: Tryptanthrin is a major active constituent of several Chinese herbal plants, such as Isatidis radix. Tryptanthrin had been demonstrated to have several beneficial pharmacological effects in vitro for human diseases, including antitumor, anti-inflammatory and antibacteria activities. In c...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyan, Xia, Jie, Zhang, Wenjing, Luo, Yao, Sun, Wenbo, Zhou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605383/
https://www.ncbi.nlm.nih.gov/pubmed/28951841
http://dx.doi.org/10.1016/j.imr.2017.05.001