Metals induce transient folding and activation of the Twister ribozyme

Twister is a small ribozyme present in almost all kingdoms of life that rapidly self-cleaves in variety of divalent metal ions. We used activity assays, bulk FRET and single-molecule FRET (smFRET) to understand how different metal ions promote folding and self-cleavage of the Oryza sativa Twister ri...

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Detalles Bibliográficos
Autores principales: Panja, Subrata, Hua, Boyang, Zegarra, Diego, Ha, Taekjip, Woodson, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605428/
https://www.ncbi.nlm.nih.gov/pubmed/28825710
http://dx.doi.org/10.1038/nchembio.2459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605428/
https://www.ncbi.nlm.nih.gov/pubmed/28825710
http://dx.doi.org/10.1038/nchembio.2459

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