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Bi-directional effects of vitamin B(12) and methotrexate on Daphnia magna fitness and genomic methylation

Here we interrogated, using three separate but complementary experimental approaches, the impact of vitamin B(12) availability and methotrexate exposure on Daphnia magna, which we hypothesised should have an opposite effect on One carbon metabolism (OCM). OCM is a vital biological process supporting...

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Detalles Bibliográficos
Autores principales: Kusari, Fitore, O’Doherty, Alan M., Hodges, Nikolas J., Wojewodzic, Marcin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605502/
https://www.ncbi.nlm.nih.gov/pubmed/28928387
http://dx.doi.org/10.1038/s41598-017-12148-2