Balance between hydration enthalpy and entropy is important for ice binding surfaces in Antifreeze Proteins

Antifreeze Proteins (AFPs) inhibit the growth of an ice crystal by binding to it. The detailed binding mechanism is, however, still not fully understood. We investigated three AFPs using Molecular Dynamics simulations in combination with Grid Inhomogeneous Solvation Theory, exploring their hydration...

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Detalles Bibliográficos
Autores principales: Schauperl, Michael, Podewitz, Maren, Ortner, Teresa S., Waibl, Franz, Thoeny, Alexander, Loerting, Thomas, Liedl, Klaus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605524/
https://www.ncbi.nlm.nih.gov/pubmed/28928396
http://dx.doi.org/10.1038/s41598-017-11982-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605524/
https://www.ncbi.nlm.nih.gov/pubmed/28928396
http://dx.doi.org/10.1038/s41598-017-11982-8

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