Polydatin inhibits mast cell-mediated allergic inflammation by targeting PI3K/Akt, MAPK, NF-κB and Nrf2/HO-1 pathways

Polydatin(PD) shows anti-allergic inflammatory effect, and this study investigated its underlying mechanisms in in vitro and in vivo models. IgE-mediated passive cutaneous anaphylaxis (PCA) and passive systemic anaphylaxis (PSA) models were used to confirm PD effect in vivo. Various signaling pathwa...

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Detalles Bibliográficos
Autores principales: Ye, Jing, Piao, Hongmei, Jiang, Jingzhi, Jin, Guangyu, Zheng, Mingyu, Yang, Jinshi, Jin, Xiang, Sun, Tianyi, Choi, Yun Ho, Li, Liangchang, Yan, Guanghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605538/
https://www.ncbi.nlm.nih.gov/pubmed/28928455
http://dx.doi.org/10.1038/s41598-017-12252-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605538/
https://www.ncbi.nlm.nih.gov/pubmed/28928455
http://dx.doi.org/10.1038/s41598-017-12252-3

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