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Immortalized N/TERT keratinocytes as an alternative cell source in 3D human epidermal models

The strong societal urge to reduce the use of experimental animals, and the biological differences between rodent and human skin, have led to the development of alternative models for healthy and diseased human skin. However, the limited availability of primary keratinocytes to generate such models...

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Detalles Bibliográficos
Autores principales: Smits, Jos P. H., Niehues, Hanna, Rikken, Gijs, van Vlijmen-Willems, Ivonne M. J. J., van de Zande, Guillaume W. H. J. F., Zeeuwen, Patrick L. J. M., Schalkwijk, Joost, van den Bogaard, Ellen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605545/
https://www.ncbi.nlm.nih.gov/pubmed/28928444
http://dx.doi.org/10.1038/s41598-017-12041-y