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Allele Age Under Non-Classical Assumptions is Clarified by an Exact Computational Markov Chain Approach
Determination of the age of an allele based on its population frequency is a well-studied problem in population genetics, for which a variety of approximations have been proposed. We present a new result that, surprisingly, allows the expectation and variance of allele age to be computed exactly (wi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605573/ https://www.ncbi.nlm.nih.gov/pubmed/28928413 http://dx.doi.org/10.1038/s41598-017-12239-0 |