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Peripheral Autoimmune Regulator Induces Exhaustion of CD4(+) and CD8(+) Effector T Cells to Attenuate Autoimmune Diabetes in Non-Obese Diabetic Mice

Autoimmune regulator (Aire) is one of the most crucial genes expressed in the thymus, where it orchestrates the promiscuous expression and presentation of tissue-specific antigens during thymocyte selection. The presence of Aire-expressing cells outside the thymus points toward its plausible extrath...

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Detalles Bibliográficos
Autores principales:	Kulshrestha, Divakar, Yeh, Li-Tzu, Chien, Ming-Wei, Chou, Feng-Cheng, Sytwu, Huey-Kang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605615/ https://www.ncbi.nlm.nih.gov/pubmed/28966617 http://dx.doi.org/10.3389/fimmu.2017.01128

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